Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592141 | 0.78 | CYP1A2 (0.44) | GABRR1HSD17B10CYP2C19EGLN1CYP1A2 | |
| SCHEMBL129934 | 0.73 | MAP3K5 (0.37) | HSD17B10MAP3K5TP53 | |
| SCHEMBL763254 | 0.73 | MAP3K5 (0.39) | HSD17B10CYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL10410694 | 0.72 | MAP3K5 (0.38) | HSD17B10MAP3K5TP53 | |
| SCHEMBL130532 | 0.70 | MAP3K5 (0.37) | HSD17B10MAP3K5TP53 | |
| SCHEMBL130807 | 0.70 | MAP3K5 (0.37) | HSD17B10MAP3K5KDM4ETP53 | |
| SCHEMBL130799 | 0.70 | MAP3K5 (0.56) | HSD17B10CYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL27533889 | 0.68 | GABRR1 (0.41) | GABRR1HSD17B10CYP2C19EGLN1CYP1A2 | |
| SCHEMBL17165345 | 0.66 | HTT (0.41) | HSD17B10CYP2C19CYP1A2 | |
| SCHEMBL9081763 | 0.66 | KDM4E (0.39) | GABRR1HSD17B10ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |