Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.39 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768291 | 1.00 | HCRTR1 (0.41) | HCRTR1HCRTR2P2RX7MOGAT2KCNH2 | |
| SCHEMBL8747990 | 0.90 | HCRTR1 (0.39) | HCRTR1HCRTR2P2RX7KCNH2EPHX2 | |
| SCHEMBL8748219 | 0.89 | HCRTR1 (0.39) | HCRTR1HCRTR2P2RX7KCNH2EPHX2 | |
| SCHEMBL8747856 | 0.89 | HCRTR1 (0.39) | HCRTR1HCRTR2P2RX7KCNH2EPHX2 | |
| SCHEMBL8747890 | 0.89 | HCRTR1 (0.39) | HCRTR1HCRTR2P2RX7KCNH2EPHX2 | |
| SCHEMBL8747913 | 0.89 | HCRTR1 (0.39) | HCRTR1HCRTR2P2RX7KCNH2PDE2A | |
| SCHEMBL8430299 | 0.88 | P2RX7 (0.41) | HCRTR1HCRTR2P2RX7KCNH2EPHX2 | |
| SCHEMBL8748231 | 0.88 | HCRTR1 (0.40) | HCRTR1HCRTR2P2RX7KCNH2EPHX2 | |
| SCHEMBL8747931 | 0.88 | HCRTR1 (0.38) | HCRTR1HCRTR2P2RX7KCNH2PDE2A | |
| SCHEMBL8747875 | 0.88 | HCRTR1 (0.38) | HCRTR1HCRTR2P2RX7KCNH2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |