SCHEMBL8768335

SCHEMBL8768335

CC(C)=CCCC(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.48
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.37
CYP3A4 P08684 3/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
TSHR P16473 1/20 0.36
UGT1A1 P22309 1/20 0.36
SQLE Q14534 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
HIF1A Q16665 1/20 0.33
EPAS1 Q99814 1/20 0.33
MAPK1 P28482 1/20 0.33
CHRNA7 P36544 1/20 0.33
STAT3 P40763 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19447805 0.75 ALOX15 (0.42) ALOX15KMT2AMEN1CYP3A4ALDH1A1
SCHEMBL23987115 0.74 ALOX15 (0.56) ALOX15KMT2AMEN1CYP3A4ALDH1A1
SCHEMBL17130891 0.74 ALOX15 (0.50) ALOX15KMT2AMEN1CYP3A4ALDH1A1
SCHEMBL676135 0.74 CD81 (0.37)
SCHEMBL3241642 0.74 CD81 (0.37)
SCHEMBL6130540 0.73
SCHEMBL583687 0.72 ALOX15 (0.60) ALOX15KMT2AMEN1CYP3A4ALDH1A1
SCHEMBL6416358 0.72
SCHEMBL13284580 0.72 ALOX15 (0.44) ALOX15KMT2AMEN1CYP3A4
SCHEMBL20085762 0.72 ALOX15 (0.43) ALOX15KMT2AMEN1CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102482495-A Personal care compositions with pituitous silicone fluids DOW CORNING 2012-05-30 CN disclosed
CN-100575408-C Fluorocarbon elastomer silicone vulcanizates DOW CORNING 2009-12-30 CN disclosed
CN-100500766-C Fluorocarbon elastomer silicone vulcanizates DOW CORNING (US) 2009-06-17 CN disclosed
CN-1976997-A Fluorocarbon elastomer silicone vulcanizates DOW CORNING (US) 2007-06-06 CN disclosed
CN-1976998-A Elastomer silicone vulcanizates DOW CORNING (US) 2007-06-06 CN disclosed
CN-1308393-C Fluorocarbon elastomer silicone vulcanizates DOW CORNING (US) 2007-04-04 CN disclosed
CN-1894310-A Fluoroplastic silicone vulcanizates DOW CORNING (US) 2007-01-10 CN disclosed
CN-1894311-A Organic elastomer silicone vulcanizates DOW CORNING (US) 2007-01-10 CN disclosed
CN-1894333-A Fluorocarbon elastomer silicone vulcanizates DOW CORNING (US) 2007-01-10 CN disclosed
CN-1286899-C Fluorocarbon elastomer polysiloxane vulcanizates DOW CORNING (US) 2006-11-29 CN disclosed
CN-1665876-A Fluorocarbon elastomer silicone vulcanizates DOW CORNING (US) 2005-09-07 CN disclosed
CN-1665875-A Fluorocarbon elastomer silicone vulcanizates DOW CORNING (US) 2005-09-07 CN disclosed
EP-0638537-B1 Process for producing cyclobutanones SUMITOMO CHEMICAL CO (JP) 1997-08-13 EP disclosed
US-5420356-A Process for producing cyclobutanones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-30 US disclosed
EP-0638537-A1 Process for producing cyclobutanones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-02-15 EP disclosed