SCHEMBL8768351

SCHEMBL8768351

CC(C)=CCC(Cl)(Cl)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862808 0.77
SCHEMBL21498160 0.75
SCHEMBL293870 0.75
SCHEMBL7138184 0.75
SCHEMBL10457457 0.74 ALOX15 (0.32) GGPS1
SCHEMBL12715718 0.74 ALOX15 (0.37) GGPS1
SCHEMBL23236471 0.72
SCHEMBL294922 0.72
SCHEMBL11299241 0.72
SCHEMBL15167313 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022606-B1 PROCESS FOR THE MANUFACTURE OF HALOGENATED HYDROCARBONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-01-12 EP claimed
US-4285778-A PREPARATION OF 1,1,1-TRIFLUORO-2,2-DICHLORO-5-METHYLHEX-4-ENE FROM A MIXTURE OF THE 4-CHLOROHEXANE DERIVATIVE, DIMETHYLFORMAMIDE, AND LITHIUM BROMIDE; BY-PRODUCT INHIBITION IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-08-25 US claimed
EP-0022606-A1 Process for the manufacture of halogenated hydrocarbons IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-21 EP claimed
US-4210611-A Halogenated hydrocarbons, useful as insecticide intermediates, and methods for their preparation IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-07-01 US claimed
EP-0638537-B1 Process for producing cyclobutanones SUMITOMO CHEMICAL CO (JP) 1997-08-13 EP disclosed
US-5420356-A Process for producing cyclobutanones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-30 US disclosed
EP-0638537-A1 Process for producing cyclobutanones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-02-15 EP disclosed
US-4864052-A 2,2-Dimethylcyclopropane-carboxylic acid derivatives SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-09-05 US disclosed
EP-0217342-A1 2,2-Dimethylcyclopropanecarboxylic acid derivatives SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-04-08 EP disclosed
EP-0022608-B1 PROCESS FOR THE PREPARATION OF CYCLOPROPANE CARBOXYLIC ACID ESTERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-07-06 EP disclosed
US-4383112-A SHIFF BASES; CATALYSTS FOR CYCLOPROPANATION OF OLEFINS BY DIAZOACETATES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1983-05-10 US disclosed
EP-0022606-B1 PROCESS FOR THE MANUFACTURE OF HALOGENATED HYDROCARBONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-01-12 EP disclosed
US-4285778-A PREPARATION OF 1,1,1-TRIFLUORO-2,2-DICHLORO-5-METHYLHEX-4-ENE FROM A MIXTURE OF THE 4-CHLOROHEXANE DERIVATIVE, DIMETHYLFORMAMIDE, AND LITHIUM BROMIDE; BY-PRODUCT INHIBITION IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-08-25 US disclosed
EP-0024797-A1 Chiral sugar complexes and process for their preparation IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-03-11 EP disclosed
EP-0024795-A1 Chiral compounds and process for their preparation IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-03-11 EP disclosed
EP-0024796-A1 Chiral amino-alcohol complexes and process for their preparation IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-03-11 EP disclosed
EP-0022606-A1 Process for the manufacture of halogenated hydrocarbons IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-21 EP disclosed
EP-0022606-A1 Process for the manufacture of halogenated hydrocarbons IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-21 EP disclosed
EP-0022608-A1 Process for the preparation of cyclopropane carboxylic acid esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-21 EP disclosed
US-4210611-A Halogenated hydrocarbons, useful as insecticide intermediates, and methods for their preparation IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-07-01 US disclosed