Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 11/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 7/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30608633 | 0.79 | AR (0.47) | CYP2C19TSHRALDH1A1ACHETDP1 | |
| SCHEMBL13673204 | 0.79 | KDM4E (0.42) | ALDH1A1CNR2ACHETDP1CNR1 | |
| SCHEMBL8767323 | 0.78 | TSHR (0.50) | CYP2C19TSHRALDH1A1CNR2 | |
| SCHEMBL22340488 | 0.77 | CNR2 (0.52) | CYP2C19ALDH1A1CNR2ACHECNR1 | |
| SCHEMBL20871893 | 0.77 | CNR2 (0.52) | CYP2C19ALDH1A1CNR2ACHECNR1 | |
| SCHEMBL13673209 | 0.76 | CA1 (0.46) | ALDH1A1CNR2ACHETDP1CNR1 | |
| SCHEMBL16978963 | 0.74 | APP (0.50) | ALDH1A1TDP1KDM4E | |
| SCHEMBL13539183 | 0.73 | CYP2C19 (0.79) | CYP2C19TSHRALDH1A1CNR2CNR1 | |
| SCHEMBL43704 | 0.72 | ALDH1A1 (0.61) | CYP2C19TSHRALDH1A1CNR2TDP1 | |
| SCHEMBL29183244 | 0.71 | CYP2C19 (0.61) | CYP2C19TSHRCNR2ACHECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638537-B1 | Process for producing cyclobutanones | SUMITOMO CHEMICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5420356-A | Process for producing cyclobutanones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0638537-A1 | Process for producing cyclobutanones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-02-15 | — | — | EP | disclosed |