Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785508 | 0.63 | CTRB1 (0.34) | CTRB1 | |
| SCHEMBL10017608 | 0.58 | CTRB1 (0.53) | CTRB1PLAU | |
| SCHEMBL10017611 | 0.54 | CTRB1 (0.49) | CTRB1PLAU | |
| SCHEMBL9541619 | 0.54 | CTRB1 (0.68) | CTRB1 | |
| SCHEMBL9602536 | 0.54 | KDM4E (0.32) | — | |
| SCHEMBL16368527 | 0.54 | — | — | |
| SCHEMBL15786373 | 0.54 | TSHR (0.35) | — | |
| SCHEMBL114258 | 0.54 | TSHR (0.35) | — | |
| SCHEMBL15780501 | 0.54 | TSHR (0.35) | — | |
| SCHEMBL18807102 | 0.54 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630364-B1 | HYDROXY DERIVATIVES OF CYCLOHEXADIENE | ZENECA LTD (GB) | 1997-08-27 | — | — | EP | disclosed |
| US-5508444-A | Cyclic compounds | ZENECA LIMITED (GB) | 1996-04-16 | — | — | US | disclosed |
| EP-0630364-A1 | HYDROXY DERIVATIVES OF CYCLOHEXADIENE. | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993017994-A1 | HYDROXY DERIVATIVES OF CYCLOHEXADIENE | ZENECA LIMITED (GB) | 1993-09-16 | — | — | WO | disclosed |