Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768452 | 1.00 | SIGMAR1 (0.36) | SIGMAR1OPRL1PDE4APDE4BPDE4C | |
| SCHEMBL8767047 | 0.99 | SIGMAR1 (0.33) | SIGMAR1OPRL1PDE4APDE4BPDE4C | |
| SCHEMBL8767054 | 0.99 | SIGMAR1 (0.33) | SIGMAR1OPRL1PDE4APDE4BPDE4C | |
| SCHEMBL8768286 | 0.95 | SIGMAR1 (0.31) | SIGMAR1OPRL1PDE4APDE4BPDE4C | |
| SCHEMBL8767240 | 0.92 | OPRL1 (0.31) | OPRL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8767897 | 0.89 | OPRL1 (0.32) | OPRL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8766980 | 0.86 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL8766976 | 0.86 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL8766971 | 0.86 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL7516241 | 0.85 | MEN1 (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |