Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10299926 | 0.83 | SIRT2 (0.58) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2458394 | 0.83 | SIRT2 (0.58) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL39113 | 0.83 | SIRT2 (0.61) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29773981 | 0.83 | SIRT2 (0.61) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1562975 | 0.83 | SIRT2 (0.61) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30140830 | 0.81 | SIRT2 (0.60) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL26598951 | 0.81 | SIRT2 (0.60) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL239516 | 0.81 | SIRT2 (0.60) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4757056 | 0.81 | HDAC3 (0.62) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11197146 | 0.80 | SIRT2 (0.52) | SIRT2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101103007-A | Amide compound | TAKEDA PHARMACEUTICAL (JP) | 2008-01-09 | — | — | CN | disclosed |
| EP-0518655-B1 | Solid phase peptide synthesis | ZENECA LTD (GB) | 1997-09-10 | — | — | EP | disclosed |