Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 2/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | FADS1 | O60427 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420390 | 0.95 | RAB9A (0.67) | RAB9ASMN1; SMN2TP53AURKAAURKB | |
| SCHEMBL8768488 | 0.89 | RAB9A (0.54) | RAB9ASMN1; SMN2TP53AURKAAURKB | |
| SCHEMBL14363287 | 0.86 | GPR17 (0.63) | RAB9ASMN1; SMN2TP53AURKAAURKB | |
| SCHEMBL9164932 | 0.85 | RAB9A (0.73) | RAB9ASMN1; SMN2TP53HTTMEN1 | |
| SCHEMBL136284 | 0.83 | CA1 (0.67) | SMN1; SMN2TP53HTTMEN1KMT2A | |
| SCHEMBL6852686 | 0.81 | RAB9A (0.66) | RAB9ASMN1; SMN2TP53HTTMEN1 | |
| SCHEMBL23796591 | 0.79 | KMT2A (0.60) | RAB9ASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL677770 | 0.79 | RAB9A (1.00) | RAB9ASMN1; SMN2TP53HTTMEN1 | |
| SCHEMBL6852748 | 0.79 | RAB9A (0.63) | RAB9ASMN1; SMN2TP53HTTMEN1 | |
| SCHEMBL6852938 | 0.79 | RAB9A (0.63) | RAB9ASMN1; SMN2TP53HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |