Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918817 | 0.86 | KMT2A (0.52) | THRBKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL28136018 | 0.77 | ALDH1A1 (0.61) | THRBKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL7449339 | 0.75 | ALDH1A1 (0.54) | THRBKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL7021656 | 0.75 | CYP1A2 (0.65) | THRBKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL7233790 | 0.75 | CYP1A2 (0.65) | THRBKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL7021651 | 0.75 | CYP1A2 (0.65) | THRBKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL2029796 | 0.75 | — | — | |
| SCHEMBL123829 | 0.75 | KMT2A (0.52) | THRBKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL7520399 | 0.75 | KMT2A (0.52) | THRBKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL7564576 | 0.73 | ALDH1A1 (0.47) | THRBKMT2AALDH1A1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | disclosed |