Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 5/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768569 | 1.00 | TGFBR1 (0.41) | TGFBR1MMEOR51E2FOLH1NAALAD2 | |
| SCHEMBL8769073 | 0.87 | — | — | |
| SCHEMBL8769068 | 0.87 | — | — | |
| SCHEMBL147537 | 0.87 | — | — | |
| SCHEMBL1923394 | 0.87 | — | — | |
| SCHEMBL8768567 | 0.80 | MME (0.36) | TGFBR1MMEOR51E2 | |
| SCHEMBL8768558 | 0.77 | TGFBR1 (0.30) | TGFBR1 | |
| SCHEMBL23052781 | 0.74 | MME (0.46) | TGFBR1MMEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL21451346 | 0.74 | MME (0.46) | TGFBR1MMEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL21451281 | 0.74 | MME (0.46) | TGFBR1MMEFOLH1NAALAD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | disclosed |