Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778305 | 0.81 | POLB (0.59) | POLBMAPTCYP19A1 | |
| SCHEMBL11781042 | 0.76 | POLB (0.40) | POLBMAPT | |
| SCHEMBL11775445 | 0.76 | POLB (0.41) | POLBMAPTCYP17A1CYP19A1 | |
| SCHEMBL8768734 | 0.72 | POLB (0.36) | POLBMAPT | |
| SCHEMBL8999961 | 0.72 | CYP19A1 (0.45) | CYP17A1DPP4CYP19A1 | |
| SCHEMBL11779179 | 0.71 | POLB (0.36) | POLBMAPT | |
| SCHEMBL8999931 | 0.71 | CYP19A1 (0.67) | CYP17A1CYP19A1 | |
| SCHEMBL17807090 | 0.71 | CYP17A1 (0.38) | POLBMAPTCYP17A1DPP4 | |
| SCHEMBL11599929 | 0.69 | CYP19A1 (0.49) | POLBMAPTCYP19A1 | |
| SCHEMBL10616333 | 0.65 | CYP19A1 (0.45) | CYP17A1DPP4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685487-B1 | A new method of preparation of a 16-beta-steroid and new intermediates of said preparation | ROUSSEL UCLAF (FR) | 1997-09-03 | — | — | EP | claimed |