Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.67 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073294 | 0.89 | CYP19A1 (0.63) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL10708164 | 0.88 | CYP19A1 (0.62) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL8999936 | 0.86 | NR3C1 (0.64) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL2118371 | 0.86 | NR3C1 (0.64) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL8999961 | 0.83 | CYP19A1 (0.45) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL11332229 | 0.83 | CYP19A1 (0.57) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL10616333 | 0.83 | CYP19A1 (0.45) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL9356635 | 0.83 | CYP19A1 (0.56) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL9356884 | 0.83 | CYP19A1 (0.56) | CYP19A1CYP17A1NR3C1 | |
| SCHEMBL8668371 | 0.81 | CYP19A1 (0.54) | CYP19A1CYP17A1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043426-C | Pregna-4,9(11), 16-triene-3,20-dione derivs. preparing process | ROUSSEL UCLAF (FR) | 1999-05-19 | — | — | CN | disclosed |
| CN-1034867-C | Process for preparing pregna-4, 9(11), 17(20) -trien-3-one derivatives | ROUSSEL UCLAF (FR) | 1997-05-14 | — | — | CN | disclosed |
| CN-1140177-A | Pregna-4,9(11), 16-triene-3,20-dione derivs. preparing process | ROUSSEL UCLAF (FR) | 1997-01-15 | — | — | CN | disclosed |
| EP-0515264-B1 | New steroid derivatives of pregna-4,9(11),17(20)-trien-3-on, their preparation, their use in the preparation of derivatives of pregna-4,9(11),16-trien-3,20-dione and intermediates therefor | ROUSSEL UCLAF (FR) | 1996-09-11 | — | — | EP | disclosed |
| EP-0515264-B1 | New steroid derivatives of pregna-4,9(11),17(20)-trien-3-on, their preparation, their use in the preparation of derivatives of pregna-4,9(11),16-trien-3,20-dione and intermediates therefor | ROUSSEL UCLAF (FR) | 1996-09-11 | — | — | EP | disclosed |
| EP-0515264-A3 | NEW STEROID DERIVATIVES OF PREGNA-4,9(11),17(20)-TRIEN-3-ON, THEIR PREPARATION, THEIR USE IN THE PREPARATION OF DERIVATIVES OF PREGNA-4,9(11),16-TRIEN-3,20-DIONE AND INTERMEDIATES THEREFOR | — | 1993-01-13 | — | — | EP | disclosed |
| EP-0515264-A2 | New steroid derivatives of pregna-4,9(11),17(20)-trien-3-on, their preparation, their use in the preparation of derivatives of pregna-4,9(11),16-trien-3,20-dione and intermediates therefor | ROUSSEL UCLAF (FR) | 1992-11-25 | — | — | EP | disclosed |
| EP-0515264-A2 | New steroid derivatives of pregna-4,9(11),17(20)-trien-3-on, their preparation, their use in the preparation of derivatives of pregna-4,9(11),16-trien-3,20-dione and intermediates therefor | ROUSSEL UCLAF (FR) | 1992-11-25 | — | — | EP | disclosed |
| EP-0127217-B1 | NEW PROCESS FOR THE PREPARATION OF 20-KETO-DELTA16-STEROIDS AND NEW INTERMEDIATE COMPOUNDS FORMED IN THIS PROCESS | GIST-BROCADES N.V. (NL) | 1988-11-02 | — | — | EP | disclosed |
| US-4551278-A | Preparation of 20-keto-Δ16 -steroids | GIST-BROCADES N.V. (NL) | 1985-11-05 | — | — | US | disclosed |
| EP-0127217-A1 | New process for the preparation of 20-keto-delta16-steroids and new intermediate compounds formed in this process | GIST-BROCADES N.V. (NL) | 1984-12-05 | — | — | EP | disclosed |
| EP-0023006-B1 | PROCESS FOR THE PREPARATION OF UNSATURATED STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-03-02 | — | — | EP | disclosed |
| US-4290963-A | HEATING ONE OF THE PREGNANE SERIES | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-09-22 | — | — | US | disclosed |
| EP-0023006-A1 | Process for the preparation of unsaturated steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-28 | — | — | EP | disclosed |