SCHEMBL8768878

SCHEMBL8768878

C=CC(=O)NC(CC)C[SiH](OC)OC

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
TAS1R3 Q7RTX0 3/20 0.36
TAS1R1 Q7RTX1 3/20 0.36
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP8 P22894 1/20 0.34
CA9 Q16790 1/20 0.34
ACACB O00763 2/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114686 0.85 TSHR (0.40) TSHRTAS1R3TAS1R1CA12CA1
SCHEMBL5170699 0.80 TSHR (0.56) TSHRTAS1R3TAS1R1CA12CA1
SCHEMBL2144271 0.79 TSHR (0.44) TSHRTAS1R3TAS1R1CA12CA1
SCHEMBL960401 0.79 CA12 (0.38) TAS1R3TAS1R1CA12CA1CA2
SCHEMBL7594351 0.77 TAS1R3 (0.51) TSHRTAS1R3TAS1R1CA12CA1
SCHEMBL963466 0.77 CA12 (0.37) CA12CA1CA2MMP1MMP2
SCHEMBL25250018 0.76 TSHR (0.52) TSHRTAS1R3TAS1R1CA12CA1
SCHEMBL2938364 0.74 TSHR (0.50) TSHRTAS1R3TAS1R1CA12CA1
SCHEMBL21909974 0.74 TSHR (0.50) TSHRTAS1R3TAS1R1CA12CA1
SCHEMBL9225320 0.73 TSHR (0.48) TSHRTAS1R3TAS1R1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250223225-A1 CONSTRUCTION MATERIAL DRY MIXES CONTAINING SOLID VINYL ESTER RESINS WACKER CHEMIE AG (DE) 2025-07-10 US disclosed
CN-111836841-B Water-soluble copolymer 瓦克化学股份公司 2022-07-29 CN disclosed
EP-0691363-B1 Polystyrene modified with a telechelic polyorganosiloxane DOW CORNING (US) 1997-09-03 EP disclosed
US-5502107-A IMPACT STRENGTH DOW CORNING CORPORATION (US) 1996-03-26 US disclosed
EP-0691363-A1 Polystyrene modified with a telechelic polyorganosiloxane DOW CORNING CORPORATION (US) 1996-01-10 EP disclosed