Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744963 | 0.89 | ALDH1A1 (0.42) | ALDH1A1PKMMAPTMAPK1LMNA | |
| SCHEMBL2589882 | 0.83 | ALDH1A1 (0.54) | ALDH1A1PKMMAPTMAPK1LMNA | |
| SCHEMBL15577645 | 0.83 | ALDH1A1 (0.54) | ALDH1A1PKMMAPTMAPK1LMNA | |
| SCHEMBL7752175 | 0.83 | MAPT (0.38) | ALDH1A1PKMMAPTMAPK1LMNA | |
| SCHEMBL7744995 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1LMNARAF1 | |
| SCHEMBL7745002 | 0.82 | ATM (0.39) | ALDH1A1MAPTMAPK1LMNAESPL1 | |
| SCHEMBL7744997 | 0.82 | ATM (0.39) | ALDH1A1MAPTMAPK1LMNAESPL1 | |
| SCHEMBL13465753 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTMAPK1LMNARAF1 | |
| SCHEMBL13268975 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTMAPK1LMNARAF1 | |
| SCHEMBL7750957 | 0.78 | ALDH1A1 (0.42) | ALDH1A1PKMMAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610384-B1 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | ABBOTT LAB (US) | 1997-09-03 | — | — | EP | disclosed |