SCHEMBL8769256

SCHEMBL8769256

O=C(O)C(F)(F)C(F)(F)OC(F)(F)C(C(F)(F)F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
ACLY P53396 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12762071 0.87 THRB (0.43) THRBACLY
SCHEMBL19484644 0.85 THRB (0.44) THRBACLY
SCHEMBL915966 0.85 THRB (0.42) THRBACLY
SCHEMBL917673 0.85 THRB (0.42) THRBACLY
SCHEMBL29554884 0.83 THRB (0.42) THRBACLY
SCHEMBL15792295 0.81 THRB (0.52) THRBACLY
Ammonia Solution, Strong SCHEMBL29599320 0.81 THRB (0.41) THRBACLY
SCHEMBL12762069 0.80 THRB (0.44) THRBACLY
SCHEMBL7263035 0.79 THRB (0.56) THRBACLY
Ammonia Solution, Strong SCHEMBL29802879 0.79 THRB (0.50) THRBACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed
WO-1996015092-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-23 WO disclosed