SCHEMBL8769308

SCHEMBL8769308

COc1ccc(Nc2c(C)cccc2C)c(C)c1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.65
ALDH1A1 P00352 2/20 0.61
ADRA2A P08913 1/20 0.53
ADRA2C P18825 1/20 0.53
ADRA1D P25100 1/20 0.53
ADRA1A P35348 1/20 0.53
ADRA1B P35368 1/20 0.53
RAPGEF4 Q8WZA2 3/20 0.50
FFAR4 Q5NUL3 1/20 0.46
RAB9A P51151 1/20 0.46
ACHE P22303 1/20 0.42
P2RX7 Q99572 1/20 0.42
OPRM1 P35372 1/20 0.42
TP53 P04637 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10639862 0.84 GAA (0.72) GAAALDH1A1ADRA2AADRA2CADRA1D
SCHEMBL11228831 0.84 GAA (0.62) GAAALDH1A1ADRA2AADRA2CADRA1D
SCHEMBL10640051 0.83 GAA (0.61) GAAALDH1A1ADRA2AADRA2CADRA1D
SCHEMBL11216820 0.82 GAA (0.60) GAAALDH1A1ADRA2AADRA2CADRA1D
SCHEMBL10338500 0.81 GAA (0.44) GAAALDH1A1RAPGEF4P2RX7TP53
SCHEMBL8942706 0.80 GAA (0.53) GAAALDH1A1RAPGEF4FFAR4
SCHEMBL502786 0.79 GAA (1.00) GAAALDH1A1ADRA2AADRA2CADRA1D
SCHEMBL7003883 0.78 GAA (0.73) GAAALDH1A1ADRA2AADRA2CADRA1D
SCHEMBL4230288 0.78 GAA (0.64) GAAALDH1A1ADRA2AADRA2CADRA1D
SCHEMBL11219654 0.78 GAA (0.64) GAAADRA2AADRA2CADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659736-B1 Process for the preparation of 4-methoxy-2,2',6'-trimethyldiphenylamine MITSUI TOATSU CHEMICALS (JP) 1997-09-17 EP claimed
US-5545751-A Process for the preparation of 4-methoxy-2,2',6'-Trimethyldiphenylamine MITSUI TOATSU CHEMICALS, INC. (JP) 1996-08-13 US claimed
EP-0659736-A1 Process for the preparation of 4-methoxy-2,2',6'-trimethyldiphenylamine MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-06-28 EP claimed
JP-9071556-A None JP disclosed
JP-9071555-A None JP disclosed
JP-9071555-A None JP disclosed
JP-9071556-A None JP disclosed
JP-7233129-A None JP disclosed
JP-7233129-A None JP disclosed
CN-1069307-C Process for the preparation of 4-methoxy-2,2',6'-trimethyldiphenylamine MITSUI CHEMICALS INC (JP) 2001-08-08 CN disclosed
EP-0659736-B1 Process for the preparation of 4-methoxy-2,2',6'-trimethyldiphenylamine MITSUI TOATSU CHEMICALS (JP) 1997-09-17 EP disclosed
US-5545751-A Process for the preparation of 4-methoxy-2,2',6'-Trimethyldiphenylamine MITSUI TOATSU CHEMICALS, INC. (JP) 1996-08-13 US disclosed
CN-1109868-A Process for the preparation of 4-methoxy-2,2',6'-trimethyldiphenylamine MITSUI TOATSU CHEMICALS (JP) 1995-10-11 CN disclosed
CN-1109868-A Process for the preparation of 4-methoxy-2,2',6'-trimethyldiphenylamine MITSUI TOATSU CHEMICALS (JP) 1995-10-11 CN disclosed
JP-H07233129-A PRODUCTION OF 4-METHOXY-2,2',6'-TRIMETHYLDIPHENYLAMINE MITSUI TOATSU CHEM INC 1995-09-05 JP disclosed
JP-H07233129-A PRODUCTION OF 4-METHOXY-2,2',6'-TRIMETHYLDIPHENYLAMINE MITSUI TOATSU CHEM INC 1995-09-05 JP disclosed
EP-0659736-A1 Process for the preparation of 4-methoxy-2,2',6'-trimethyldiphenylamine MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-06-28 EP disclosed
EP-0659736-A1 Process for the preparation of 4-methoxy-2,2',6'-trimethyldiphenylamine MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-06-28 EP disclosed
US-4910183-A With an acidic developer APPLETON PAPERS INC. (US) 1990-03-20 US disclosed
US-4837210-A PRESSURE SENSITIVE OR HEAT SENSITIVE ELEMENTS APPLETON PAPERS INC. (US) 1989-06-06 US disclosed