Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flumetsulam SCHEMBL54906 | 0.88 | TSHR (0.40) | GAASMN1; SMN2HTR6TSHR | |
| Flumetsulam SCHEMBL20723426 | 0.86 | TSHR (0.39) | GAASMN1; SMN2HTR6TSHR | |
| Flumetsulam SCHEMBL20723449 | 0.86 | TSHR (0.39) | GAASMN1; SMN2HTR6TSHR | |
| SCHEMBL11056313 | 0.86 | TSHR (0.35) | HTR6TSHR | |
| SCHEMBL9831797 | 0.85 | KMT2A (0.47) | GAAPOLBSMN1; SMN2SLC22A12TSHR | |
| SCHEMBL9832538 | 0.84 | TSHR (0.38) | SMN1; SMN2HTR6TSHR | |
| Flumetsulam SCHEMBL22587375 | 0.82 | TSHR (0.37) | GAASMN1; SMN2HTR6TSHR | |
| SCHEMBL9832548 | 0.82 | HTR6 (0.39) | HTR6TSHRKDM4E | |
| SCHEMBL8762523 | 0.82 | TSHR (0.46) | PKMGAAHTR6TSHRKDM4E | |
| SCHEMBL9832187 | 0.81 | TSHR (0.36) | HTR6SLC22A12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784431-A1 | SYNERGISTIC ACTIVE SUBSTANCE HERBICIDE COMBINATIONS WITH 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-5-(2-CHLOROPROPIONAMIDO)-4-NITROPYRAZOL | BAYER AG (DE) | 1997-07-23 | — | — | EP | claimed |
| WO-1996010333-A1 | SYNERGISTIC ACTIVE SUBSTANCE HERBICIDE COMBINATIONS WITH 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-5-(2-CHLOROPROPIONAMIDO)-4-NITROPYRAZOL | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-11 | — | — | WO | claimed |