Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 5/20 | 0.80 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | CDC25A | P30304 | 1/20 | 0.66 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037770 | 1.00 | VDR (0.80) | VDRMAPTSMN1; SMN2SREBF1MEN1 | |
| SCHEMBL18023064 | 1.00 | VDR (0.80) | VDRMAPTSMN1; SMN2SREBF1MEN1 | |
| SCHEMBL12517774 | 1.00 | VDR (0.80) | VDRMAPTSMN1; SMN2SREBF1MEN1 | |
| SCHEMBL18021746 | 0.91 | VDR (0.72) | VDRMAPTSMN1; SMN2SREBF1MEN1 | |
| SCHEMBL10349035 | 0.89 | VDR (0.74) | VDRMAPTSMN1; SMN2SREBF1PGR | |
| Maxacalcitol SCHEMBL24066887 | 0.89 | VDR (1.00) | VDRMAPTSMN1; SMN2PGRADORA3 | |
| Maxacalcitol SCHEMBL7084224 | 0.89 | VDR (1.00) | VDRMAPTSMN1; SMN2PGRADORA3 | |
| Maxacalcitol SCHEMBL20460962 | 0.89 | VDR (1.00) | VDRMAPTSMN1; SMN2PGRADORA3 | |
| Maxacalcitol SCHEMBL20460998 | 0.89 | VDR (1.00) | VDRMAPTSMN1; SMN2PGRADORA3 | |
| Maxacalcitol SCHEMBL5153671 | 0.89 | VDR (1.00) | VDRMAPTSMN1; SMN2PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2028114-A | — | — | None | — | — | JP | disclosed |
| EP-0619304-B1 | 22-OXACHOLECALCIFEROL DERIVATIVE AND PRODUCTION THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-09-10 | — | — | EP | disclosed |
| US-5436401-A | 22-oxacholecalciferol derivative and process for preparing the same | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0619304-A1 | 22-OXACHOLECALCIFEROL DERIVATIVE AND PRODUCTION THEREOF | Chugai Seiyaku Kabushiki Kaisha (JP) | 1994-10-12 | — | — | EP | disclosed |
| JP-H0228114-A | REMEDY FOR NEPHRITIS | CHUGAI PHARMACEUT CO LTD | 1990-01-30 | — | — | JP | disclosed |