SCHEMBL8769664

SCHEMBL8769664

C=CC[SiH](C)CCCCC

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.42
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.32
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5968746 0.98 TSHR (0.46) TSHRALDH1A1THRBFAAH
SCHEMBL8769540 0.93
SCHEMBL278975 0.82
SCHEMBL438729 0.78 TSHR (0.44) TSHRALDH1A1THRBFAAH
SCHEMBL437976 0.78 TSHR (0.44) TSHRALDH1A1THRBFAAH
SCHEMBL29188260 0.76 TSHR (0.48) TSHRALDH1A1THRBFAAH
SCHEMBL29156637 0.76 TSHR (0.48) TSHRALDH1A1THRBFAAH
SCHEMBL6897883 0.76 TSHR (0.48) TSHRALDH1A1THRBFAAH
SCHEMBL8639212 0.76 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL7040757 0.74 TSHR (0.41) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604401-B1 Production of a catalyst component for producing crystalline polymers CHISSO CORP (JP) 1997-09-24 EP disclosed
EP-0395391-B1 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0564004-B1 A highly stereoregular polypropylene CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0404519-B1 A process for producing a high-stiffness polypropylene CHISSO CORP (JP) 1996-08-07 EP disclosed
EP-0468373-B1 Process for the preparation of aryl-alkyl-methylsilanes HOECHST SCHERING AGREVO GMBH (DE) 1996-04-17 EP disclosed
EP-0604401-A2 Production of a catalyst component for producing crystalline polymers CHISSO CORPORATION (JP) 1994-06-29 EP disclosed
EP-0564004-A1 A highly stereoregular polypropylene CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5173540-A Coordination catalyst comprising titanium compound, organo aluminum compound electron donor and a polymer support; transparent, voidless films produced CHISSO CORPORATION (JP) 1992-12-22 US disclosed
EP-0468373-A1 Process for the preparation of aryl-alkyl-methylsilanes Hoechst Schering AgrEvo GmbH (DE) 1992-01-29 EP disclosed
US-5077341-A Using coordination catalyst CHISSO CORPORATION (JP) 1991-12-31 US disclosed
EP-0395391-A2 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORPORATION (JP) 1990-10-31 EP disclosed