Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437976 | 0.98 | TSHR (0.44) | TSHRALDH1A1THRBLMNAHSD17B10 | |
| SCHEMBL438729 | 0.93 | TSHR (0.44) | TSHRALDH1A1THRBLMNAHSD17B10 | |
| SCHEMBL6894712 | 0.90 | TSHR (0.43) | TSHRALDH1A1LMNA | |
| SCHEMBL8770263 | 0.88 | TSHR (0.41) | TSHRALDH1A1THRBSMN1; SMN2 | |
| Fluoride SCHEMBL27912823 | 0.88 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL5968559 | 0.85 | TSHR (0.43) | TSHRALDH1A1LMNA | |
| SCHEMBL5881430 | 0.79 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL5968746 | 0.79 | TSHR (0.46) | TSHRALDH1A1THRBFAAHZDHHC20 | |
| SCHEMBL26666755 | 0.79 | TSHR (0.73) | TSHRALDH1A1THRBLMNAFAAH | |
| SCHEMBL6740317 | 0.77 | TSHR (0.44) | TSHRALDH1A1THRBFAAHZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098926-B1 | CROSS-LINKABLE HYPERBRANCHED POLYMERS, METHOD FOR THE PRODUCTION AND USE OF THE SAME | BAYER MATERIALSCIENCE AG (DE) | 2004-03-03 | — | — | EP | disclosed |
| EP-1098926-A1 | CROSS-LINKABLE HYPERBRANCHED POLYMERS, METHOD FOR THE PRODUCTION AND USE OF THE SAME | Bayer Aktiengesellschaft (DE) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000002954-A1 | CROSS-LINKABLE HYPERBRANCHED POLYMERS, METHOD FOR THE PRODUCTION AND USE OF THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-20 | — | — | WO | disclosed |