SCHEMBL8769768

SCHEMBL8769768

C=C(CCSCCCCCC)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.53
HSD17B10 Q99714 2/20 0.53
GMNN O75496 1/20 0.53
TP53 P04637 1/20 0.53
POLB P06746 1/20 0.53
MAPT P10636 1/20 0.53
CYP2C9 P11712 1/20 0.53
BLM P54132 1/20 0.53
CES2 O00748 3/20 0.48
PLA2G4B P0C869 1/20 0.45
FAAH O00519 4/20 0.43
CES1 P23141 4/20 0.43
PLA2G6 O60733 1/20 0.43
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43
PGGT1B P53609 1/20 0.43
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 6/20 0.42
PPARD Q03181 6/20 0.42
PPARA Q07869 6/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7062182 1.00 THRB (0.53) THRBHSD17B10GMNNTP53POLB
SCHEMBL7649870 0.93 THRB (0.53) THRBHSD17B10GMNNTP53POLB
SCHEMBL11604256 0.92 HSD17B10 (0.42) THRBHSD17B10GMNNTP53POLB
SCHEMBL6379639 0.83 THRB (0.66) THRBHSD17B10GMNNTP53POLB
SCHEMBL9705486 0.83 THRB (0.66) THRBHSD17B10GMNNTP53POLB
SCHEMBL11123745 0.82 HSD17B10 (0.52) HSD17B10TSHRALDH1A1TDP1ALOX15
Methane SCHEMBL4056603 0.81 THRB (0.63) THRBHSD17B10GMNNTP53POLB
Methane SCHEMBL6845687 0.81 THRB (0.63) THRBHSD17B10GMNNTP53POLB
Methane SCHEMBL8329266 0.81 THRB (0.63) THRBHSD17B10GMNNTP53POLB
SCHEMBL18832148 0.81 HSD17B10 (0.57) THRBHSD17B10GMNNTP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0796890-A1 Vulcanizable acrylic rubber composition ENICHEM S.p.A. (IT) 1997-09-24 EP disclosed
EP-0287560-B1 RUBBERY ACRYLIC POLYMER, LATEX AND PREPARATION THEREOF GOODRICH CO B F (US) 1996-08-21 EP disclosed
EP-0264903-B1 Rubbery acrylic polymer, latex and preparation thereof GOODRICH CO B F (US) 1996-04-10 EP disclosed
EP-0264869-B1 Nonwoven fabric with an acrylate interpolymer binder and a process of making the nonwoven fabric GOODRICH CO B F (US) 1994-07-13 EP disclosed
EP-0264871-B1 A film of rubbery latex, articles of manufacture made from the film, and a process of making the film GOODRICH CO B F (US) 1994-07-13 EP disclosed
US-5166227-A Mixing silicon dioxide with a latex and spray drying to give a filler with improved physical properties and tensile strength ZEON CHEMICALS USA, INC. (US) 1992-11-24 US disclosed
US-5017630-A Polymer aloy, spray drying ZEON CHEMICALS USA, INC. (US) 1991-05-21 US disclosed
EP-0287560-A4 RUBBERY ACRYLIC POLYMER, LATEX AND PREPARATION THEREOF. GOODRICH CO B F (US) 1989-02-22 EP disclosed
EP-0287560-A1 RUBBERY ACRYLIC POLYMER, LATEX AND PREPARATION THEREOF. GOODRICH CO B F (US) 1988-10-26 EP disclosed
EP-0264871-A2 A film of rubbery latex, articles of manufacture made from the film, and a process of making the film THE B.F. GOODRICH COMPANY (US) 1988-04-27 EP disclosed
EP-0264903-A2 Rubbery acrylic polymer, latex and preparation thereof THE B.F. GOODRICH COMPANY (US) 1988-04-27 EP disclosed
EP-0264869-A2 Nonwoven fabric with an acrylate interpolymer binder and a process of making the nonwoven fabric THE B.F. GOODRICH COMPANY (US) 1988-04-27 EP disclosed
WO-1988002759-A1 RUBBERY ACRYLIC POLYMER, LATEX AND PREPARATION THEREOF THE B.F. GOODRICH COMPANY (US) 1988-04-21 WO disclosed
EP-0094601-B1 VULCANIZABLE ACRYLATE RUBBER COMPOSITIONS The B.F. GOODRICH Company (US) 1986-09-03 EP disclosed
US-4434274-A IMPROVED SCORCH-CURE RATE BALANCE THE B. F. GOODRICH COMPANY (US) 1984-02-28 US disclosed
US-4405758-A Vulcanizable acrylate rubber compositions THE B. F. GOODRICH COMPANY (US) 1983-09-20 US disclosed
US-4399262-A WITH MALOGEN AND CARBOXY CURE SITES, VULANIZATION, 2,3-DIMERCAPTO-1,3,4-THIADIAZOLE, METAL TETRAALKYL THIURAM SULFIDE COMPOUND THE B. F. GOODRICH COMPANY (US) 1983-08-16 US disclosed