Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL9321454 | 1.00 | TSHR (0.33) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| SCHEMBL225103 | 0.91 | — | — | |
| Water SCHEMBL3180232 | 0.87 | TSHR (0.36) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| SCHEMBL21052521 | 0.83 | TSHR (0.33) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| SCHEMBL8946186 | 0.77 | — | — | |
| SCHEMBL11236418 | 0.75 | TSHR (0.33) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| SCHEMBL11119115 | 0.74 | MGLL (0.30) | — | |
| SCHEMBL6271453 | 0.72 | — | — | |
| SCHEMBL16673711 | 0.72 | MEN1 (0.38) | — | |
| SCHEMBL528387 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027209-A1 | NEW SUBSTITUTED 19-NOR-PREGNANE DERIVATIVES | LABORATOIRE THERAMEX (MC) | 1997-07-31 | — | — | WO | disclosed |
| EP-0785211-A1 | New substituted 19-nor-pregnane derivatives | LABORATOIRE THERAMEX (MC) | 1997-07-23 | — | — | EP | disclosed |