SCHEMBL8769838

SCHEMBL8769838

Cc1c(C)c(N=C=O)c(N=C=O)c(C(C)C)c1C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1459319 0.89 CYP3A4 (0.34) CYP3A4GABRA1GABRB2
SCHEMBL1128050 0.88 CYP3A4 (0.33) CYP3A4GABRA1GABRB2
SCHEMBL2814949 0.82 CYP3A4 (0.44) CYP3A4GABRA1GABRB2
SCHEMBL112221 0.79 CYP3A4 (0.42) CYP3A4GABRA1GABRB2
SCHEMBL403882 0.77 GABRA1 (0.38) CYP3A4GABRA1GABRB2
SCHEMBL7747680 0.77 CYP3A4 (0.44) CYP3A4GABRA1GABRB2
Water SCHEMBL27841311 0.75 GABRA1 (0.37) CYP3A4GABRA1GABRB2
SCHEMBL28344084 0.74 CYP3A4 (0.42) CYP3A4GABRA1GABRB2
SCHEMBL57779 0.74 CYP3A4 (0.46) CYP3A4GABRA1GABRB2
SCHEMBL29010423 0.73 CYP3A4 (0.32) CYP3A4GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0652906-B1 METHOD OF MODIFYING POLYMERS HENKEL KGAA (DE) 1997-09-17 EP disclosed
EP-0652906-A1 METHOD OF MODIFYING POLYMERS. HENKEL KGAA (DE) 1995-05-17 EP disclosed
WO-1994003523-A1 METHOD OF MODIFYING POLYMERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-02-17 WO disclosed