Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 5/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760327 | 0.86 | LMNA (0.69) | ESR1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL21276838 | 0.86 | LMNA (0.69) | ESR1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL8366649 | 0.86 | LMNA (0.69) | ESR1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL6466708 | 0.81 | LMNA (0.72) | ESR1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL544801 | 0.81 | LMNA (0.72) | ESR1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL544802 | 0.81 | LMNA (0.72) | ESR1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL16140032 | 0.81 | LMNA (0.72) | ESR1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL5679557 | 0.81 | LMNA (0.72) | ESR1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL12473458 | 0.81 | LMNA (0.72) | ESR1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL8769805 | 0.80 | ESR1 (0.68) | ESR1LMNAHSD17B1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027209-A1 | NEW SUBSTITUTED 19-NOR-PREGNANE DERIVATIVES | LABORATOIRE THERAMEX (MC) | 1997-07-31 | — | — | WO | disclosed |
| EP-0785211-A1 | New substituted 19-nor-pregnane derivatives | LABORATOIRE THERAMEX (MC) | 1997-07-23 | — | — | EP | disclosed |