Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770389 | 0.85 | PTGER1 (0.47) | PTGER1MAOAMAOBKMT2APTGS1 | |
| SCHEMBL8770492 | 0.82 | PTGER1 (0.58) | PTGER1MAOAMAOBKMT2APTGS1 | |
| SCHEMBL8770413 | 0.79 | PTGER1 (0.52) | PTGER1MAOAMAOBKMT2A | |
| SCHEMBL8770553 | 0.78 | PTGER1 (0.53) | PTGER1MAOAMAOBKMT2APTGS1 | |
| SCHEMBL8770509 | 0.77 | PTGER1 (0.58) | PTGER1MAOAMAOBKMT2APTGS1 | |
| SCHEMBL8770468 | 0.75 | KMT2A (0.40) | PTGER1MAOAMAOBKMT2APTGS1 | |
| SCHEMBL8770407 | 0.74 | PTGER1 (0.49) | PTGER1MAOAMAOBPTGS1 | |
| SCHEMBL6188862 | 0.72 | KMT2A (0.79) | KMT2APTGS1 | |
| SCHEMBL8770489 | 0.72 | PTGER1 (0.47) | PTGER1MAOAMAOBPTGS1 | |
| SCHEMBL3981310 | 0.71 | KMT2A (0.68) | KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566175-B1 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-08-06 | — | — | EP | claimed |
| US-5371106-A | Reacting arylacetic acid derivative with haloketone derivative in a solvent in presence of stoichiometric amount of base to form phenacyl ester derivative which is cyclized in situ by adding base | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-12-06 | — | — | US | claimed |
| EP-0566175-B1 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-08-06 | — | — | EP | disclosed |