Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770553 | 0.94 | PTGER1 (0.53) | PTGER1MAOAMAOBPTGS2KDM4E | |
| SCHEMBL8770492 | 0.91 | PTGER1 (0.58) | PTGER1MAOAMAOBPTGS2PTGS1 | |
| SCHEMBL8770509 | 0.91 | PTGER1 (0.58) | PTGER1MAOAMAOBPTGS2KDM4E | |
| SCHEMBL8770413 | 0.87 | PTGER1 (0.52) | PTGER1MAOAMAOBCCR5 | |
| SCHEMBL8770489 | 0.86 | PTGER1 (0.47) | PTGER1MAOAMAOBPTGS2PTGS1 | |
| SCHEMBL8770494 | 0.86 | PTGER1 (0.60) | PTGER1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL8770409 | 0.84 | MAOB (0.52) | MAOAMAOBPTGS1 | |
| SCHEMBL8770706 | 0.82 | PTGER1 (0.44) | PTGER1MAOAMAOBPTGS2PTGS1 | |
| SCHEMBL8770371 | 0.80 | PTGER1 (0.47) | PTGER1PTGS2POLBPTGS1 | |
| SCHEMBL8770448 | 0.80 | MAOA (0.51) | PTGER1MAOAMAOBPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566175-B1 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-08-06 | — | — | EP | claimed |
| US-5371106-A | Reacting arylacetic acid derivative with haloketone derivative in a solvent in presence of stoichiometric amount of base to form phenacyl ester derivative which is cyclized in situ by adding base | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-12-06 | — | — | US | claimed |
| EP-0566175-B1 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-08-06 | — | — | EP | disclosed |