Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770407 | 0.84 | PTGER1 (0.49) | MAOBMAOAPTGS1 | |
| SCHEMBL8770374 | 0.79 | MEN1 (0.53) | MAOBMAOAPTGS1KMT2ANR4A2 | |
| SCHEMBL8770413 | 0.78 | PTGER1 (0.52) | MAOBMAOAKMT2A | |
| SCHEMBL3981310 | 0.77 | KMT2A (0.68) | PTGS1KMT2A | |
| SCHEMBL8770553 | 0.77 | PTGER1 (0.53) | MAOBMAOAPTGS1KMT2ARXRA | |
| SCHEMBL1558316 | 0.77 | PTGS1 (0.64) | MAOBMAOAPTGS1KMT2A | |
| SCHEMBL1556919 | 0.76 | KMT2A (0.51) | MAOBMAOAPTGS1KMT2A | |
| SCHEMBL28741980 | 0.75 | PTGS1 (0.74) | PTGS1KMT2A | |
| SCHEMBL8770386 | 0.75 | PTGS1 (0.52) | MAOBPTGS1 | |
| SCHEMBL8770492 | 0.74 | PTGER1 (0.58) | MAOBMAOAPTGS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566175-B1 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-08-06 | — | — | EP | claimed |
| US-5371106-A | Reacting arylacetic acid derivative with haloketone derivative in a solvent in presence of stoichiometric amount of base to form phenacyl ester derivative which is cyclized in situ by adding base | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-12-06 | — | — | US | claimed |
| EP-0566175-B1 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-08-06 | — | — | EP | disclosed |