Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531316 | 0.93 | GAA (0.53) | ALDH1A1GAAMAPK1KDM4EMEN1 | |
| SCHEMBL13215292 | 0.88 | GAA (0.41) | ALDH1A1GAAMAPK1PTGDR2KDM4E | |
| SCHEMBL13623313 | 0.87 | MAPK1 (0.40) | ALDH1A1MAPK1PTGDR2KDM4EHPGD | |
| SCHEMBL8770380 | 0.87 | AAK1 (0.40) | ALDH1A1MAPK1PTGDR2KDM4EHPGD | |
| SCHEMBL4855128 | 0.87 | MAPK1 (0.51) | ALDH1A1GAAMAPK1PTGDR2KDM4E | |
| SCHEMBL13665133 | 0.83 | ALDH1A1 (0.50) | ALDH1A1GAAMAPK1KDM4EHPGD | |
| SCHEMBL27539557 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPK1KDM4EHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL8474144 | 0.81 | ALDH1A1 (0.51) | ALDH1A1GAAMAPK1PTGDR2KDM4E | |
| SCHEMBL7284623 | 0.80 | TSHR (0.51) | ALDH1A1GAAMAPK1KDM4EHPGD | |
| SCHEMBL13215511 | 0.80 | PSEN1 (0.38) | ALDH1A1GAAMAPK1PTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |