Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.75 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.75 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.75 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.75 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.75 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.75 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.75 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | NAAA | Q02083 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27339421 | 1.00 | MAPK1 (0.76) | MAPK1HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL10659200 | 0.94 | MAPK1 (0.86) | MAPK1HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL10865398 | 0.94 | MAPK1 (0.86) | MAPK1HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL5655215 | 0.94 | MAPK1 (0.86) | MAPK1HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL1231651 | 0.94 | MAPK1 (0.86) | MAPK1HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL950223 | 0.92 | MAPK1 (0.83) | MAPK1HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL8770687 | 0.89 | HDAC6 (0.73) | MAPK1HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL8770814 | 0.89 | MAPK1 (0.69) | MAPK1HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL3596135 | 0.88 | MAPK1 (0.81) | MAPK1HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL3081575 | 0.88 | MAPK1 (0.81) | MAPK1HDAC6HDAC1HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018633-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1996-06-20 | — | — | WO | disclosed |