Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NAAA | Q02083 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3596135 | 1.00 | MAPK1 (0.81) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL10865398 | 0.94 | MAPK1 (0.86) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL1231651 | 0.94 | MAPK1 (0.86) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL5655215 | 0.94 | MAPK1 (0.86) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL10659200 | 0.94 | MAPK1 (0.86) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL950223 | 0.92 | MAPK1 (0.83) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL428355 | 0.90 | MAPK1 (1.00) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL6387697 | 0.88 | MAPK1 (0.81) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL27339421 | 0.88 | MAPK1 (0.76) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL8770694 | 0.88 | MAPK1 (0.76) | MAPK1HDAC6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577670-B1 | Latent reactive polymers with biologically active moieties, method of preparing a biocompatible coating and bulk material, and use | SURMODICS INC (US) | 2015-01-28 | — | — | EP | disclosed |
| EP-2148201-A1 | Latent reactive polymers with biologically active moieties | SurModics, Inc. (US) | 2010-01-27 | — | — | EP | disclosed |
| EP-1064292-B1 | PHOTOACTIVATABLE NUCLEIC ACID DERIVATIVES | SURMODICS INC (US) | 2006-09-20 | — | — | EP | disclosed |
| EP-1577670-A2 | Latent reactive polymers with biologically active moieties | SurModics, Inc. (US) | 2005-09-21 | — | — | EP | disclosed |
| EP-1534420-A1 | HIGH DENSITY ARRAYS | SurModics, Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| EP-1003561-B1 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SURMODICS INC (US) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004020085-A1 | HIGH DENSITY ARRAYS | SURMODICS, INC. (US) | 2004-03-11 | — | — | WO | disclosed |
| US-20030181423-A1 | Reagent activated to form bulk material or brought into contact with surface of previously formed biomaterial and activated to form coating; pendent bioactive groups function by promoting attachment of specific molecules to surface | CLAPPER DAVID L (US) | 2003-09-25 | — | — | US | disclosed |
| US-20030082604-A1 | High density arrays | SURMODICS, INC. | 2003-05-01 | — | — | US | disclosed |
| US-6514734-B1 | Pendent bioactive groups function by promoting attachment of specific molecules or cells to the bulk material or coated surface; bioactive groups can include proteins, peptides, carbohydrates, and nucleic acids; e.g. neurons to electrodes | SURMODICS, INC. | 2003-02-04 | — | — | US | disclosed |
| US-6506895-B2 | Oligonucleotide for use in generation of nucleic acid chips | SURMODICS, INC. | 2003-01-14 | — | — | US | disclosed |
| US-20020086989-A1 | PHOTOACTIVATABLE NUCLEIC ACID DERIVATIVES | SURMODICS IVD, INC. | 2002-07-04 | — | — | US | disclosed |
| EP-1064292-A1 | PHOTOACTIVATABLE NUCLEIC ACID DERIVATIVES | SurModics, Inc. (US) | 2001-01-03 | — | — | EP | disclosed |
| US-6121027-A | FOR COATING BIOMATERIAL SURFACES AND FORMING A CROSSLINKED BIOMATERIAL | SURMODICS, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-1003561-A2 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SurModics, Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999043688-A1 | PHOTOACTIVATABLE NUCLEIC ACID DERIVATIVES | SURMODICS, INC. (US) | 1999-09-02 | — | — | WO | disclosed |
| WO-1999008717-A2 | LATENT REACTIVE POLYMERS WITH BIOLOGICALLY ACTIVE MOIETIES | SURMODICS, INC. (US) | 1999-02-25 | — | — | WO | disclosed |