SCHEMBL8770717

SCHEMBL8770717

Cc1cccc2c1C=CC2[SiH3]

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
CYP2A6 P11509 2/20 0.32
CYP1A2 P05177 1/20 0.32
HTR2C P28335 2/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9143901 0.98 ALDH1A1 (0.31) ALDH1A1CYP2A6CYP1A2HTR2CCA1
SCHEMBL9145287 0.98 ALDH1A1 (0.31) ALDH1A1CYP2A6CYP1A2HTR2CCA1
Lithium SCHEMBL9143917 0.98 ALDH1A1 (0.31) ALDH1A1CYP2A6CYP1A2HTR2CCA1
SCHEMBL9145296 0.98 ALDH1A1 (0.31) ALDH1A1CYP2A6CYP1A2HTR2CCA1
SCHEMBL1025201 0.78 ALDH1A1 (0.36) ALDH1A1CYP2A6CYP1A2HTR2CCA1
Hydrochloric Acid SCHEMBL9440324 0.75 HTR2C (0.34) ALDH1A1CYP2A6CYP1A2HTR2CCA1
SCHEMBL8024877 0.75 CYP1A2 (0.32) ALDH1A1CYP2A6CYP1A2HTR2CCA1
SCHEMBL8770676 0.75 HTR2A (0.30) HTR2C
SCHEMBL6454970 0.73 HTR2C (0.31) ALDH1A1CYP2A6CYP1A2HTR2CCA1
SCHEMBL7056170 0.73 HTR2C (0.32) ALDH1A1CYP2A6CYP1A2HTR2CCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0569249-B1 Ethylene/alpha-olefin copolymers NIPPON OIL CO LTD (JP) 1997-08-06 EP disclosed
EP-0569249-A2 Ethylene/alpha-olefin copolymers NIPPON OIL COMPANY, LIMITED (JP) 1993-11-10 EP disclosed