Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770468 | 0.83 | KMT2A (0.40) | PTGER1KMT2APTGS1 | |
| SCHEMBL8770480 | 0.83 | KMT2A (0.50) | PTGER1HPGDKMT2AALDH1A1PTGS1 | |
| SCHEMBL8770371 | 0.83 | PTGER1 (0.47) | PTGER1L3MBTL1KMT2APOLBMEN1 | |
| SCHEMBL8770486 | 0.81 | PTGER1 (0.46) | PTGER1KMT2AMAPTPTGS1 | |
| SCHEMBL8770509 | 0.77 | PTGER1 (0.58) | PTGER1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8770492 | 0.75 | PTGER1 (0.58) | PTGER1KMT2APTGS1 | |
| SCHEMBL8770494 | 0.75 | PTGER1 (0.60) | PTGER1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8770382 | 0.74 | PTGER1 (0.48) | PTGER1PTGS1 | |
| SCHEMBL8770553 | 0.74 | PTGER1 (0.53) | PTGER1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8770374 | 0.73 | MEN1 (0.53) | HPGDSMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566175-B1 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-08-06 | — | — | EP | disclosed |
| US-5371106-A | Reacting arylacetic acid derivative with haloketone derivative in a solvent in presence of stoichiometric amount of base to form phenacyl ester derivative which is cyclized in situ by adding base | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-12-06 | — | — | US | disclosed |
| EP-0566175-A2 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-10-20 | — | — | EP | disclosed |