Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 6/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770386 | 0.86 | PTGS1 (0.52) | PTGS1PGRNR3C2PTGS2 | |
| SCHEMBL8770371 | 0.86 | PTGER1 (0.47) | PTGER1PTGS1PTGS2 | |
| SCHEMBL8770553 | 0.82 | PTGER1 (0.53) | PTGER1PTGS1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL8770492 | 0.82 | PTGER1 (0.58) | PTGER1PTGS1CYP2C9PTGS2 | |
| SCHEMBL8770509 | 0.79 | PTGER1 (0.58) | PTGER1PTGS1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL8770407 | 0.78 | PTGER1 (0.49) | PTGER1PTGS1PTGS2 | |
| SCHEMBL8770489 | 0.78 | PTGER1 (0.47) | PTGER1PTGS1PTGS2 | |
| SCHEMBL8770448 | 0.77 | MAOA (0.51) | PTGER1PTGS1PTGS2 | |
| SCHEMBL8770486 | 0.77 | PTGER1 (0.46) | PTGER1PTGS1PTGS2 | |
| SCHEMBL8770494 | 0.77 | PTGER1 (0.60) | PTGER1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566175-B1 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-08-06 | — | — | EP | claimed |
| US-5371106-A | Reacting arylacetic acid derivative with haloketone derivative in a solvent in presence of stoichiometric amount of base to form phenacyl ester derivative which is cyclized in situ by adding base | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-12-06 | — | — | US | claimed |
| EP-0566175-B1 | 3,4-Diaryl (5H)-furan-2-one based compounds with fungicide activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-08-06 | — | — | EP | disclosed |
| US-5371106-A | Reacting arylacetic acid derivative with haloketone derivative in a solvent in presence of stoichiometric amount of base to form phenacyl ester derivative which is cyclized in situ by adding base | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-12-06 | — | — | US | disclosed |