Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770498 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBTSHRSMN1; SMN2MAPT | |
| SCHEMBL8770742 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBTSHRSMN1; SMN2MAPT | |
| SCHEMBL8770626 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBTSHRSMN1; SMN2MAPT | |
| SCHEMBL8770604 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBTSHRSMN1; SMN2MAPT | |
| SCHEMBL10635243 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBTSHRSMN1; SMN2MAPT | |
| SCHEMBL10691305 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBTSHRSMN1; SMN2MAPT | |
| SCHEMBL8770571 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBTSHRSMN1; SMN2MAPT | |
| SCHEMBL8770555 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBTSHRSMN1; SMN2MAPT | |
| SCHEMBL7230903 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBTSHRSMN1; SMN2MAPT | |
| SCHEMBL7234564 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBTSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798366-A2 | Lubricant | NEMATEL Dr. Rudolf Eidenschink (DE) | 1997-10-01 | — | — | EP | disclosed |
| US-4734522-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-03-29 | — | — | US | disclosed |
| US-4578210-A | Carbocyclic six-membered ring compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-03-25 | — | — | US | disclosed |
| EP-0134576-A2 | Carbocyclic six-membered ring compounds | MERCK PATENT GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |