⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2256202 | 0.75 | — | — | |
| SCHEMBL8465271 | 0.73 | — | — | |
| SCHEMBL22551299 | 0.72 | CYP2C19 (0.60) | — | |
| SCHEMBL6444227 | 0.72 | — | — | |
| SCHEMBL7879535 | 0.71 | — | — | |
| SCHEMBL13395969 | 0.69 | TRPA1 (0.35) | — | |
| SCHEMBL10484076 | 0.69 | — | — | |
| SCHEMBL15791167 | 0.69 | — | — | |
| SCHEMBL10403365 | 0.69 | — | — | |
| SCHEMBL10403366 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630514-B2 | Process and intermediates for the preparation of pyroxasulfone | ADAMA AGAN LTD. (IL) | 2026-05-19 | — | — | US | claimed |
| EP-4003964-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE | ADAMA AGAN LTD (IL) | 2024-09-18 | — | — | EP | claimed |
| US-20220267279-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE | ADAMA AGAN LTD. (IL) | 2022-08-25 | — | — | US | claimed |
| CN-114450270-A | Preparation method and intermediate of xaflufen | 安道麦阿甘有限公司 | 2022-05-06 | — | — | CN | claimed |
| US-12630514-B2 | Process and intermediates for the preparation of pyroxasulfone | ADAMA AGAN LTD. (IL) | 2026-05-19 | — | — | US | disclosed |
| US-20260022113-A1 | Process for the Preparation of Pyroxasulfone | ATTICUS LLC (US) | 2026-01-22 | — | — | US | disclosed |
| CN-114450270-B | Preparation method and intermediate of metazopyr | 安道麦阿甘有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-115784992-B | Preparation method and application of pyrazole mercapto-methylated derivative | 山东润博生物科技有限公司 | 2025-01-28 | — | — | CN | disclosed |
| EP-4003964-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE | ADAMA AGAN LTD (IL) | 2024-09-18 | — | — | EP | disclosed |
| US-11708530-B2 | Organic ligands for templatable mesoscale nanocapsules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-25 | — | — | US | disclosed |
| CN-115784992-A | Preparation method and application of pyrazole mercaptomethylated derivative | 山东润博生物科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| US-20220267279-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE | ADAMA AGAN LTD. (IL) | 2022-08-25 | — | — | US | disclosed |
| EP-0550574-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992005180-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |
| EP-0074861-B1 | AMINOCYCLOPENTANE ESTERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1986-08-27 | — | — | EP | disclosed |
| US-4410521-A | ANTICOAGULANTS, BRONCHODILATOR AGENTS | GLAXO GROUP LIMITED (GB) | 1983-10-18 | — | — | US | disclosed |
| US-4399136-A | Pyrazolopyridazine antihypertensives | HOFFMANN-LA ROCHE INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0074861-A1 | Aminocyclopentane esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | disclosed |
| EP-0042100-A1 | Pyrazolopyridazine derivatives, intermediates and processes for their preparation, and medicaments containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-12-23 | — | — | EP | disclosed |
| US-3984404-A | Acylthiomethyl esters of cephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |