SCHEMBL8770944

SCHEMBL8770944

CN(C)c1nnc(S)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14093855 0.80
SCHEMBL10821178 0.72 CYP3A4 (0.37)
SCHEMBL12596374 0.70
Hydrogen Sulfide SCHEMBL5357620 0.70
SCHEMBL2517414 0.68
SCHEMBL11420903 0.68
SCHEMBL29412221 0.66
SCHEMBL18427626 0.65 CYP3A4 (0.55)
SCHEMBL349852 0.63
SCHEMBL10371931 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4229573-A BACTERICIDES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-10-21 US claimed
EP-0796263-A1 CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-09-24 EP disclosed
WO-1996017850-A1 CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-06-13 WO disclosed
US-4415566-A ANTIBIOTICS; BACTERIOSTATS; BACTERICIDES BOEHRINGER INGELHEIM GMBH (DE) 1983-11-15 US disclosed
EP-0022494-B1 BETA-LACTAM-COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1983-02-23 EP disclosed
EP-0022494-A1 Beta-lactam-compounds, process for their preparation and therapeutic agents containing them Dr. Karl Thomae GmbH (DE) 1981-01-21 EP disclosed