⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936155 | 0.72 | LMNA (0.56) | — | |
| SCHEMBL2517414 | 0.70 | — | — | |
| SCHEMBL8770944 | 0.70 | — | — | |
| SCHEMBL11420903 | 0.70 | — | — | |
| SCHEMBL18427626 | 0.67 | CYP3A4 (0.55) | — | |
| SCHEMBL2210464 | 0.63 | GAA (0.33) | — | |
| SCHEMBL7050276 | 0.61 | — | — | |
| SCHEMBL298980 | 0.61 | — | — | |
| SCHEMBL15074839 | 0.59 | NOS1 (0.44) | — | |
| SCHEMBL12263493 | 0.59 | NPC1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113554-A1 | QUINOLINE DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-11 | — | — | WO | disclosed |
| US-20110112151-A1 | COMPOUND CAPABLE OF INHIBITING 11-BETA HYDROXYSTERIOD DEHYDROGENASE | STERIX LIMITED (GB) | 2011-05-12 | — | — | US | disclosed |
| US-20110112151-A1 | COMPOUND CAPABLE OF INHIBITING 11-BETA HYDROXYSTERIOD DEHYDROGENASE | STERIX LIMITED (GB) | 2011-05-12 | — | — | US | disclosed |
| WO-2009106817-A2 | COMPOUND | STERIX LIMITED (GB) | 2009-09-03 | — | — | WO | disclosed |