SCHEMBL8771256

SCHEMBL8771256

C=CCC[C@H]1CC[C@H]([C@H]2CC[C@H](c3ccc(F)c(F)c3)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.35
USP5 P45974 2/20 0.34
HDAC6 Q9UBN7 1/20 0.34
CCR2 P41597 1/20 0.34
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
USP30 Q70CQ3 1/20 0.33
DGAT1 O75907 1/20 0.32
SOAT1 P35610 1/20 0.32
OPRL1 P41146 4/20 0.32
CYP2C9 P11712 2/20 0.31
CNR1 P21554 1/20 0.30
ESR1 P03372 1/20 0.30
CYP3A4 P08684 1/20 0.30
HCRTR2 O43614 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771239 1.00 ESR2 (0.35) ESR2USP5HDAC6CCR2HTR2A
SCHEMBL6686674 1.00 ESR2 (0.35) ESR2USP5HDAC6CCR2HTR2A
SCHEMBL9136179 0.99 ESR2 (0.34) ESR2USP5HDAC6CCR2HTR2A
SCHEMBL9253967 0.94 ESR2 (0.36) ESR2USP5HDAC6CCR2HTR2A
SCHEMBL9253959 0.94 ESR2 (0.36) ESR2USP5HDAC6CCR2HTR2A
SCHEMBL9253972 0.94 ESR2 (0.36) ESR2USP5HDAC6CCR2HTR2A
SCHEMBL19850904 0.90 ESR2 (0.35) ESR2CCR2DGAT1SOAT1CYP2C9
SCHEMBL8024986 0.90 ESR2 (0.35) ESR2CCR2DGAT1SOAT1CYP2C9
SCHEMBL8040838 0.89 CCR2 (0.32) USP5HDAC6CCR2DGAT1SOAT1
SCHEMBL8040836 0.89 CCR2 (0.32) USP5HDAC6CCR2DGAT1SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0799878-A1 Liquid crystal compositions and liquid crystal display elements containing same Shin-Etsu Chemical Co., Ltd. (JP) 1997-10-08 EP disclosed