SCHEMBL877154

SCHEMBL877154

Cc1nsc(S)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12150579 0.71
SCHEMBL11430040 0.67
SCHEMBL2730482 0.67
SCHEMBL10779167 0.67
SCHEMBL6503632 0.65
SCHEMBL6530304 0.65
SCHEMBL46520 0.65
SCHEMBL12808016 0.65
SCHEMBL547688 0.65
SCHEMBL8999497 0.63 RXFP1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030082101-A1 Accelerators for increasing the rate of formation of free radicals and reactive oxygen species CAVALIER DISCOVERY 2003-05-01 US claimed
US-4861769-A Cephem compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-08-29 US claimed
EP-0192210-A2 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-08-27 EP claimed
EP-0022245-A2 Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation CIBA-GEIGY AG (CH) 1981-01-14 EP claimed
US-4229573-A BACTERICIDES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-10-21 US claimed
US-4172197-A BACTERICIDES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-10-23 US claimed
US-4147693-A βLactam antibiotics and process for their use BAYER AKTIENGESELLSCHAFT (DE) 1979-04-03 US claimed
US-4144391-A REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE ELI LILLY AND COMPANY (US) 1979-03-13 US claimed
US-4118562-A ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1978-10-03 US claimed
US-4094872-A 7-(β-Aminoacylamino)-3-heterocyclic-thiomethyl-3-cephem-4-carboxylic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-06-13 US claimed
US-4093804-A ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1978-06-06 US claimed
US-4093802-A ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1978-06-06 US claimed
US-4034090-A ANTIBACTERIAL RHONE-POULENC INDUSTRIES (FR) 1977-07-05 US claimed
US-4001225-A Pyridyl substituted 7-αesters of 3 heterothio 7-acetamido cephalosporanic acids FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-01-04 US claimed
US-3948904-A ANTIBIOTICS YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) 1976-04-06 US claimed
WO-2022266711-A1 SUBSTITUTED AMIDOBENZIMIDAZOLE DIMERS AS STING MODULATORS Aculeus Therapeutics Pty Ltd (AU) 2022-12-29 WO disclosed
US-10443016-B2 Lubricating oil composition for gear oil JXTG NIPPON OIL & ENERGY CORPORATION (JP) 2019-10-15 US disclosed
US-3950330-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1976-04-13 US disclosed
US-3948904-A ANTIBIOTICS YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) 1976-04-06 US disclosed
US-3931170-A BACTERICIDE E. R. SQUIBB & SONS, INC. (US) 1976-01-06 US disclosed