⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656333 | 0.69 | — | — | |
| SCHEMBL2730482 | 0.67 | — | — | |
| SCHEMBL877154 | 0.65 | — | — | |
| SCHEMBL547688 | 0.65 | — | — | |
| SCHEMBL12808016 | 0.65 | — | — | |
| SCHEMBL12150579 | 0.65 | — | — | |
| SCHEMBL9852100 | 0.61 | — | — | |
| SCHEMBL12045423 | 0.61 | — | — | |
| SCHEMBL21547825 | 0.61 | — | — | |
| SCHEMBL21547826 | 0.59 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884103-B2 | such as N-(4-Chloro-phenyl)-2-methyl-2-phenylmethanesulfonylamino-3-(4-[1,2,4]triazol-1-yl-phenoxy)-propionamide, used for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-08 | — | — | US | claimed |
| EP-1513802-B1 | ALPHA-SULFONYLAMINO-ACETONITRILES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-19 | — | — | EP | claimed |
| US-7368479-B2 | Alpha-sulfonylamino-acetonitriles | SYNGENTA CROP PROTECTION, INC. (US) | 2008-05-06 | — | — | US | claimed |
| US-20070155748-A1 | N-sulfonyl-alpha-amino-acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2007-07-05 | — | — | US | claimed |
| JP-2007504108-A | — | — | 2007-03-01 | — | — | JP | claimed |
| EP-1660441-A2 | N-SULFONYL-ALPHA-AMINO-ACID DERIVATIVES | Syngenta Participations AG (CH) | 2006-05-31 | — | — | EP | claimed |
| US-20050234125-A1 | Alpha-sulfonylamino-acetonitriles | SYNGENTA CROP PROTECTION AG (CH) | 2005-10-20 | — | — | US | claimed |
| EP-1513802-A1 | ALPHA-SULFONYLAMINO-ACETONITRILES | Syngenta Participations AG (CH) | 2005-03-16 | — | — | EP | claimed |
| WO-2005021490-A2 | N-SULFONYL-α-AMINO-ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-03-10 | — | — | WO | claimed |
| WO-2004000797-A1 | ALPHA-SULFONYLAMINO-ACETONITRILES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-12-31 | — | — | WO | claimed |
| WO-2024028603-A1 | PYRROLIDINE-2-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES | HEPTARES THERAPEUTICS LIMITED (GB) | 2024-02-08 | — | — | WO | disclosed |
| WO-2024028604-A1 | MORPHOLINE-3-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES | HEPTARES THERAPEUTICS LIMITED (GB) | 2024-02-08 | — | — | WO | disclosed |
| US-11072582-B2 | Substituted pyrrolidines as G-protein coupled receptor 43 agonists | EPICS THERAPEUTICS (BE) | 2021-07-27 | — | — | US | disclosed |
| WO-2021069927-A1 | PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2021-04-15 | — | — | WO | disclosed |
| US-20200347016-A1 | SUBSTITUTED PYRROLIDINES AS G-PROTEIN COUPLED RECEPTOR 43 AGONISTS | EPICS THERAPEUTICS (BE) | 2020-11-05 | — | — | US | disclosed |
| US-5481013-A | INSECTICIDES, MITICIDES, CROPS | CIBA-GEIGY CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| US-5326901-A | 3-butenoic acid derivatives as intermediates for pesticides | CIBA-GEIGY CORPORATION (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0577555-A1 | Derivatives of carboxylic acids | CIBA-GEIGY AG (CH) | 1994-01-05 | — | — | EP | disclosed |
| EP-0468927-A2 | Derivatives of carboxymethylcyclopropane | CIBA-GEIGY AG (CH) | 1992-01-29 | — | — | EP | disclosed |
| EP-0467840-A2 | Derivatives of cyclopropyl acetic acid | CIBA-GEIGY AG (CH) | 1992-01-22 | — | — | EP | disclosed |