Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 14/20 | 0.56 |
| ▸ | RARB | P10826 | 11/20 | 0.56 |
| ▸ | RARG | P13631 | 8/20 | 0.56 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | BLVRB | P30043 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654688 | 0.86 | RARA (0.72) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL4653632 | 0.79 | RARA (0.63) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL6292560 | 0.74 | RARA (0.68) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL8771833 | 0.74 | RARB (0.52) | RARARARBRARG | |
| SCHEMBL6086904 | 0.73 | RARB (0.49) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL4652495 | 0.72 | RARA (0.68) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL6239917 | 0.72 | RARB (1.00) | RARARARBRARG | |
| SCHEMBL6294092 | 0.72 | RARA (0.52) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL4757231 | 0.71 | RARA (1.00) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL8771827 | 0.70 | RARA (0.78) | RARARARBRARGCYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661259-B1 | Substituted (5,6)-dihydronaphthalenyl compounds having retinoid-like activity | BRISTOL MYERS SQUIBB CO (US) | 1997-10-08 | — | — | EP | disclosed |