Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 7/20 | 0.49 |
| ▸ | FNTA | P49354 | 7/20 | 0.48 |
| ▸ | FNTB | P49356 | 5/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771809 | 0.86 | FNTA (0.50) | GGPS1FNTAFNTBPGGT1B | |
| SCHEMBL8909861 | 0.82 | FNTA (0.46) | FNTAFNTBPGGT1B | |
| SCHEMBL8771640 | 0.79 | GGPS1 (0.48) | GGPS1FNTAFNTB | |
| SCHEMBL7626203 | 0.77 | FNTA (0.56) | GGPS1FNTAFNTB | |
| SCHEMBL7626199 | 0.77 | FNTA (0.56) | GGPS1FNTAFNTB | |
| SCHEMBL8771696 | 0.77 | FNTA (0.49) | GGPS1FNTAFNTBPGGT1B | |
| SCHEMBL9064176 | 0.74 | GGPS1 (0.54) | GGPS1FNTAFNTB | |
| SCHEMBL6550101 | 0.74 | GGPS1 (0.54) | GGPS1FNTAFNTB | |
| SCHEMBL7626511 | 0.74 | GGPS1 (0.54) | GGPS1FNTAFNTB | |
| SCHEMBL8539459 | 0.74 | GGPS1 (0.54) | GGPS1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686159-B1 | FARNESYL:PROTEIN TRANSFERASE INHIBITORS AS ANTICANCER AGENTS | MERRELL PHARMA INC (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5665715-A | Farnesyl:protein transferase inhibitors as anticancer agents | MERRELL PHARMACEUTICALS INC. (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0686159-A1 | FARNESYL:PROTEIN TRANSFERASE INHIBITORS AS ANTICANCER AGENTS | MERRELL DOW PHARMA (US) | 1995-12-13 | — | — | EP | disclosed |
| US-5463181-A | Farnesyl: protein transferase inhibitors as anticancer agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-10-31 | — | — | US | disclosed |