Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.49 |
| ▸ | FNTB | P49356 | 5/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771714 | 0.85 | FNTA (0.50) | FNTAFNTBGGPS1PGGT1B | |
| SCHEMBL8909997 | 0.80 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL8771790 | 0.78 | FNTA (0.49) | FNTAFNTBGGPS1 | |
| SCHEMBL8771667 | 0.77 | GGPS1 (0.49) | FNTAFNTBGGPS1PGGT1B | |
| SCHEMBL9394077 | 0.76 | GGPS1 (0.48) | FNTAFNTBGGPS1PGGT1B | |
| SCHEMBL8771707 | 0.74 | FNTA (0.62) | FNTAFNTBGGPS1PGGT1B | |
| SCHEMBL8909848 | 0.73 | KDM4E (0.50) | FNTAFNTB | |
| SCHEMBL8909842 | 0.73 | KDM4E (0.50) | FNTAFNTB | |
| SCHEMBL8771682 | 0.72 | GGPS1 (0.54) | FNTAFNTBGGPS1PGGT1B | |
| SCHEMBL8909844 | 0.71 | KDM4E (0.49) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686159-B1 | FARNESYL:PROTEIN TRANSFERASE INHIBITORS AS ANTICANCER AGENTS | MERRELL PHARMA INC (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5665715-A | Farnesyl:protein transferase inhibitors as anticancer agents | MERRELL PHARMACEUTICALS INC. (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0686159-A1 | FARNESYL:PROTEIN TRANSFERASE INHIBITORS AS ANTICANCER AGENTS | MERRELL DOW PHARMA (US) | 1995-12-13 | — | — | EP | disclosed |
| US-5463181-A | Farnesyl: protein transferase inhibitors as anticancer agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-10-31 | — | — | US | disclosed |