SCHEMBL8771883

SCHEMBL8771883

O=[C]OC(=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12032915 0.74
SCHEMBL10457021 0.72
SCHEMBL532333 0.70
SCHEMBL3500822 0.67 CA2 (0.35)
SCHEMBL52 0.67 CA2 (0.35)
SCHEMBL27623481 0.67 CA2 (0.35)
Hydrogen Peroxide SCHEMBL2051538 0.65 CA2 (0.33)
SCHEMBL3945654 0.65 CA2 (0.33)
SCHEMBL3945657 0.65 CA2 (0.33)
Hydrochloric Acid SCHEMBL8958370 0.65 CA2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0638563-B1 Aminoaryl-1,3-oxazin-2,4-diones BAYER AG (DE) 1997-10-15 EP disclosed
US-5593944-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
EP-0638563-A1 Aminoaryl-1,3-oxazin-2,4-diones BAYER AG (DE) 1995-02-15 EP disclosed
EP-0248414-B1 ARALKYL IMIDAZOLE DERIVATIVES CIBA-GEIGY AG (CH) 1992-09-23 EP disclosed
US-5098922-A Anticonvulsants CIBA-GEIGY CORPORATION (US) 1992-03-24 US disclosed
US-5045556-A Aralkyl-4H-1,2,4-triazole derivatives CIBA-GEIGY CORPORATION (US) 1991-09-03 US disclosed
EP-0267147-B1 ARALKYL-4H-1,2,4-TRIAZOLE DERIVATIVES CIBA-GEIGY AG (CH) 1991-08-07 EP disclosed
EP-0199262-B1 FLUORINATED BENZYL TRIAZOLE COMPOUNDS CIBA-GEIGY AG (CH) 1991-02-27 EP disclosed
US-4851424-A 1-Phenyl-lower alkyl-imidazole 4- or 5-carboxamide compounds which are useful in the treatment of epilepsy CIBA-GEIGY CORPORATION (US) 1989-07-25 US disclosed
US-4804661-A ANALGESICS CIBA-GEIGY CORPORATION (US) 1989-02-14 US disclosed
US-4789680-A Aralkyltriazole compounds CIBA-GEIGY CORPORATION (US) 1988-12-06 US disclosed
EP-0267147-A1 Aralkyl-4H-1,2,4-triazole derivatives CIBA-GEIGY AG (CH) 1988-05-11 EP disclosed
EP-0248414-A2 Aralkyl imidazole derivatives CIBA-GEIGY AG (CH) 1987-12-09 EP disclosed
EP-0199262-A2 Fluorinated benzyl triazole compounds CIBA-GEIGY AG (CH) 1986-10-29 EP disclosed
US-4559349-A TREATMENT OF PHYCHOSIS CIBA GEIGY CORPORATION (US) 1985-12-17 US disclosed
EP-0114347-A2 Aralkyl-triazole compounds CIBA-GEIGY AG (CH) 1984-08-01 EP disclosed