Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186721 | 0.78 | HRH3 (0.51) | MAPK1HRH3ALDH1A1KMT2AHPGD | |
| SCHEMBL1295721 | 0.78 | HRH3 (0.51) | MAPK1HRH3ALDH1A1KMT2AHPGD | |
| SCHEMBL28492122 | 0.78 | HRH3 (0.51) | MAPK1HRH3ALDH1A1KMT2AHPGD | |
| SCHEMBL3780480 | 0.76 | MAPK1 (0.41) | MAPK1HRH3NFKB1NFKB2RELA | |
| SCHEMBL15497807 | 0.76 | ALDH1A1 (0.43) | HRH3NFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL6283782 | 0.75 | MAPK1 (0.46) | MAPK1ALDH1A1KMT2ACHRM2CHRM1 | |
| SCHEMBL1139839 | 0.74 | MAPK1 (0.40) | MAPK1HRH3NFKB1NFKB2RELA | |
| SCHEMBL10058228 | 0.74 | MAPK1 (0.40) | MAPK1HRH3NFKB1NFKB2RELA | |
| SCHEMBL11013935 | 0.73 | MAPK1 (0.42) | MAPK1NFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL31368099 | 0.73 | MAPK1 (0.42) | MAPK1HRH3NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601572-B1 | Method for producing a spherical ion exchange resin | MITSUBISHI CHEM CORP (JP) | 1997-10-15 | — | — | EP | disclosed |
| EP-0601572-A2 | Method for producing a spherical ion exchange resin | Mitsubishi Chemical Corporation (JP) | 1994-06-15 | — | — | EP | disclosed |