Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.50 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 7/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL11579913 | 0.98 | TSHR (0.52) | TSHRALDH1A1LMNAAPEX1FFAR3 | |
| Glycinebetaine SCHEMBL20337331 | 0.87 | TSHR (0.48) | TSHRALDH1A1LMNAAPEX1FFAR3 | |
| Glycinebetaine SCHEMBL9281697 | 0.87 | TSHR (0.55) | TSHRALDH1A1LMNAAPEX1FFAR3 | |
| Betaine SCHEMBL31467313 | 0.87 | — | — | |
| Glycinebetaine SCHEMBL2803780 | 0.87 | TSHR (0.53) | TSHRALDH1A1LMNAAPEX1FFAR3 | |
| Glycinebetaine SCHEMBL4900209 | 0.87 | — | — | |
| Glycinebetaine SCHEMBL8678519 | 0.87 | TSHR (0.53) | TSHRALDH1A1LMNAAPEX1FFAR3 | |
| Glycinebetaine SCHEMBL7739 | 0.87 | — | — | |
| Betaine SCHEMBL677352 | 0.85 | TSHR (0.70) | TSHRALDH1A1LMNAAPEX1FFAR3 | |
| Glycinebetaine SCHEMBL15813100 | 0.85 | TSHR (0.55) | TSHRALDH1A1LMNAAPEX1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56169658-A | — | — | None | — | — | JP | disclosed |
| JP-56169658-A | — | — | None | — | — | JP | disclosed |
| CN-100526916-C | Multilayer optical adhesive and article | 3M INNOVATIVE PROPERTIES CO (US) | 2009-08-12 | — | — | CN | disclosed |
| CN-1875296-A | Multilayer optical adhesives and articles | 3M INNOVATIVE PROPERTIES CO (US) | 2006-12-06 | — | — | CN | disclosed |
| EP-0797644-A1 | REMOVABLE PRESSURE SENSITIVE ADHESIVE AND ARTICLE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018701-A1 | REMOVABLE PRESSURE SENSITIVE ADHESIVE AND ARTICLE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-06-20 | — | — | WO | disclosed |
| JP-S56169658-A | PREPARATION OF PROPIONATE BETAINE CRYSTAL | FUJI PHOTO FILM CO LTD | 1981-12-26 | — | — | JP | disclosed |
| JP-S56169658-A | PREPARATION OF PROPIONATE BETAINE CRYSTAL | FUJI PHOTO FILM CO LTD | 1981-12-26 | — | — | JP | disclosed |