Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649379 | 0.87 | POLB (0.41) | BRD4SRD5A1SRD5A2CMA1AHR | |
| SCHEMBL8649374 | 0.81 | POLB (0.44) | BRD4CMA1AHRTDP2DYRK1A | |
| SCHEMBL27640660 | 0.80 | BRD4 (0.43) | BRD4SRD5A1SRD5A2CMA1AHR | |
| SCHEMBL650500 | 0.71 | BRD4 (0.48) | BRD4SRD5A1SRD5A2CMA1AHR | |
| SCHEMBL31394401 | 0.71 | BRD4 (0.46) | BRD4CMA1AHRTDP2TGM2 | |
| SCHEMBL19586030 | 0.69 | SRD5A1 (0.42) | SRD5A1SRD5A2CMA1AHRTDP2 | |
| SCHEMBL8650338 | 0.67 | POLB (0.38) | CCNB2CDK1CCNB1CCNB3MEN1 | |
| SCHEMBL240792 | 0.67 | TDP2 (0.41) | SRD5A1SRD5A2CMA1AHRTDP2 | |
| SCHEMBL30758541 | 0.67 | TDP2 (0.41) | SRD5A1SRD5A2CMA1AHRTDP2 | |
| SCHEMBL7214466 | 0.65 | BRD4 (0.52) | BRD4SRD5A1SRD5A2CMA1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801060-A1 | Heterocyclic Beta-3 Adrenergenic Agonists | PFIZER INC. (US) | 1997-10-15 | — | — | EP | disclosed |