Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567291 | 1.00 | TSHR (0.46) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL3112619 | 0.84 | TSHR (0.44) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL3120570 | 0.82 | TSHR (0.41) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL3124658 | 0.81 | TSHR (0.46) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL892063 | 0.80 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL3039671 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL7046566 | 0.78 | TSHR (0.38) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL2936701 | 0.78 | TSHR (0.52) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL104256 | 0.78 | TSHR (0.52) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL399787 | 0.78 | TSHR (0.52) | TSHRALDH1A1USP2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463689-B1 | Preparation of polymers of carbon monoxide with olefinically unsaturated compounds | SHELL INT RESEARCH (NL) | 1997-10-15 | — | — | EP | disclosed |
| EP-0272727-B1 | NOVEL POLYMERS OF CARBON MONOXIDE AND ALPHA-OLEFINICALLY UNSATURATED COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-10-28 | — | — | EP | disclosed |
| EP-0463689-A2 | Preparation of polymers of carbon monoxide with olefinically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-01-02 | — | — | EP | disclosed |
| EP-0272727-A2 | Novel polymers of carbon monoxide and alpha-olefinically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-29 | — | — | EP | disclosed |