SCHEMBL8772314

SCHEMBL8772314

CCCCCCc1cc(C(CCC)c2cc(C)c(O)c(CCCCCC)c2)cc(C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 6/20 0.43
PTGS2 P35354 5/20 0.43
TYR P14679 2/20 0.43
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
BID P55957 3/20 0.36
MCL1 Q07820 3/20 0.36
BCL2L1 Q07817 2/20 0.36
BAK1 Q16611 2/20 0.36
KAT8 Q9H7Z6 2/20 0.36
ESR1 P03372 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772337 0.84 ALOX5 (0.45) ALOX5PTGS2TYRMEN1TP53
SCHEMBL28138685 0.84 TYR (0.42) ALOX5PTGS2TYRMEN1TP53
SCHEMBL12653592 0.81 TP53 (0.44) ALOX5PTGS2TYRMEN1TP53
SCHEMBL20520221 0.80 ESR1 (0.45) ESR1
SCHEMBL20520192 0.80 ESR1 (0.45) ESR1
SCHEMBL20520281 0.80 ESR1 (0.45) ESR1
SCHEMBL5709944 0.80 ESR1 (0.45) ESR1
SCHEMBL20520248 0.80 ESR1 (0.45) ESR1
SCHEMBL11186793 0.80 ESR1 (0.45) ESR1
SCHEMBL20520289 0.80 ESR1 (0.45) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed